LD50
LD50 is the amount of a hazardous
substance that results in the death of 50 percent of the individuals exposed.
LD50 is commonly measured by exposing rats or mice to
increasing amounts of the toxic substance until a dosage is reached that kills
half the exposed animals within a certain time period (usually fourteen days).
Dan M. Sullivan
Table 1. Toxicity rating for humans (70 kg [154
lb.] body weight).
TOXICITY RATING FOR HUMANS (70 KG
BODY WEIGHT) |
|
Rating/Class |
Dose |
SOURCE: Gosselin, et al. (1984). Clinical Toxicology of Commercial
Products. Baltimore: Williams & Wilkens. |
|
6. Super toxic |
<5 mg/kg |
5. Extremely toxic |
550 mg/kg |
4. Very toxic |
50500 mg/kg |
3. Moderately toxic |
0.55 g/kg |
2. Slightly toxic |
515 g/kg |
1. Practically nontoxic |
>15 g/kg |
Although traditional investigations
into the toxicity of chemicals in the natural environment have focused on
animals, the toxicity of agrichemical and environmental
pollutants to plants (phytotoxicity) has gained
interest. Despite being well documented in literature, phytotoxicity
is measured in various ways by agronomists and plant scientists; a standard quantification unit
is therefore difficult to devise
. Poison Control Emergency Number: 1-800-222-1222
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